{"id":15230,"date":"2012-08-22T01:30:00","date_gmt":"2012-08-21T23:30:00","guid":{"rendered":"http:\/\/www.fedaiisf.it\/farmaci-off-label-la-mayo-clinic-svela-quello-che-di-solito-non-si-sa-su-questi-medicinali\/"},"modified":"2012-08-22T01:30:00","modified_gmt":"2012-08-21T23:30:00","slug":"farmaci-off-label-la-mayo-clinic-svela-quello-che-di-solito-non-si-sa-su-questi-medicinali","status":"publish","type":"post","link":"https:\/\/www.fedaiisf.it\/en\/farmaci-off-label-la-mayo-clinic-svela-quello-che-di-solito-non-si-sa-su-questi-medicinali\/","title":{"rendered":"Off-label drugs. The Mayo Clinic reveals what is usually not known about these drugs"},"content":{"rendered":"<p class=\"MsoNormal\" style=\"text-align: left; line-height: normal; margin: 0cm 0cm 10pt; background: white; mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; mso-outline-level: 3\"><b><i><span style=\"font-family: &quot;Georgia&quot;,&quot;serif&quot;; color: black; font-size: 12pt; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-fareast-language: IT\">Not everyone knows them, but many use them, even if they are not aware that they are off-label drugs. That is, those medicines which in clinical practice are used for different uses (by pathology, population or dosage) from those indicated by the Medicines Agencies. <a target=\"_blank\" href=\"http:\/\/www.quotidianosanita.it\/allegati\/allegato4701289.pdf\" rel=\"noopener\"><span style=\"color: blue\">Here you are<\/span><\/a> what is usually not known about them.<\/span><\/i><\/b><b><span style=\"font-family: &quot;Georgia&quot;,&quot;serif&quot;; color: black; font-size: 12pt; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-fareast-language: IT\"><\/p>\n<p><\/span><\/b><\/p>\n<p class=\"MsoNormal\" style=\"text-align: left; line-height: normal; margin: 0cm 0cm 10pt; background: white; mso-margin-top-alt: auto; mso-margin-bottom-alt: auto\"><font size=\"3\"><b><span style=\"font-family: &quot;Georgia&quot;,&quot;serif&quot;; color: #c10c05; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: Arial; mso-fareast-language: IT\">22 AUG<\/span><\/b><span style=\"font-family: &quot;Arial&quot;,&quot;sans-serif&quot;; color: #333333; mso-fareast-font-family: 'Times New Roman'; mso-fareast-language: IT\"> <\/span><\/font><span style=\"font-family: &quot;Arial&quot;,&quot;sans-serif&quot;; mso-fareast-font-family: 'Times New Roman'; mso-fareast-language: IT\"><font size=\"3\">\u2013 If some patients have heard of drugs prescribed &#039;off-label&#039;, ie outside their indication for use, not all those who use them know they do. For this the Mayo Clinic has published in its journal, <i>Mayo Clinics Proceedings<\/i>, a series of notions, questions and answers on the matter, in order to help patients better understand what these medicines are and why they are used for some pathologies even if according to official use they should be prescribed for others. \u201cWe have no power over the decisions of the Food and Drug Administration \u2013 he explained <b>Christopher Wittich<\/b> of Mayo \u2013 but we have the ability to educate staff and patients on the use of off-label drugs, so that both the doctors who prescribe them and those who take them know the risks and benefits\u201d.<\/font><span style=\"color: #333333\"><\/p>\n<p> <b><font size=\"3\">Here are the highlights of the <\/font><a target=\"_blank\" href=\"http:\/\/www.quotidianosanita.it\/allegati\/allegato4701289.pdf\" rel=\"noopener\"><span style=\"color: blue\"><font size=\"3\">Work:<\/font><\/span><\/a><font size=\"3\"> <\/font><\/b><br \/> <\/span><font size=\"3\">\u2013 the use of off-label drugs is common. If we consider the most commonly prescribed drugs, about 1 in five are used off-label, but when we consider the population of pediatric patients who have just been discharged from hospitals, the percentage of young patients who use at least one drug outside the indication for use rises to 79%;<br \/> \u2013 the use of off-label drugs may become the most common treatment for a given condition. For example, some antidepressants are not approved by the FDA as a treatment for neuropathic pain, yet some of these drugs are considered a first choice treatment option;<br \/> \u2013 an example of a widely used off-label drug is morphine in the treatment of pain in pediatric patients, as well as in children, inhaled bronchodilators, antimicrobials, anticonvulsants,<\/p>","protected":false},"excerpt":{"rendered":"<p>Non tutti li conoscono, ma molti li usano, pur non consapevoli che si tratta di farmaci off label. Cio&egrave; quei medicinali che nella pratica clinica sono impiegati per usi diversi (per patologia, popolazione o posologia) da quelli indicati dalle Agenzie del Farmaco. Ecco quello che di solito non si sa su di loro. 22 AGO &hellip;<\/p>","protected":false},"author":1,"featured_media":9846,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[90],"tags":[],"class_list":["post-15230","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fedaiisf-archivio-storico"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts\/15230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/comments?post=15230"}],"version-history":[{"count":0,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts\/15230\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/media\/9846"}],"wp:attachment":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/media?parent=15230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/categories?post=15230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/tags?post=15230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}