{"id":15696,"date":"2012-10-31T03:30:00","date_gmt":"2012-10-31T02:30:00","guid":{"rendered":"http:\/\/www.fedaiisf.it\/anticorpi-monoclonali-medici-diffidano-di-generici\/"},"modified":"2012-10-31T03:30:00","modified_gmt":"2012-10-31T02:30:00","slug":"anticorpi-monoclonali-medici-diffidano-di-generici","status":"publish","type":"post","link":"https:\/\/www.fedaiisf.it\/en\/anticorpi-monoclonali-medici-diffidano-di-generici\/","title":{"rendered":"Monoclonal antibodies, doctors are wary of generics"},"content":{"rendered":"<p class=\"MsoNormal\" style=\"text-align: left; line-height: normal; margin: 0cm 0cm 0pt; text-autospace: ; mso-layout-grid-align: none\"><span style=\"font-family: BookAntiqua; color: #212120; font-size: 12pt; mso-bidi-font-family: BookAntiqua\"><font face=\"Calibri\">The prospect of switching from the &#039;name brand&#039; monoclonal antibody to its equivalent version is not an automatic step for all oncologists. Indeed, according to a survey by the BioTends Research Group, when biosimilars of intelligent anticancer drugs such as rituximab (blockbuster from the Swiss Roche) become available, a good percentage of oncologists may have some hesitation in making the &#039;switch&#039;.<\/p>\n<p><\/font><\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: left; line-height: normal; margin: 0cm 0cm 0pt; text-autospace: ; mso-layout-grid-align: none\"><span style=\"font-family: BookAntiqua; color: #212120; font-size: 12pt; mso-bidi-font-family: BookAntiqua\"><font face=\"Calibri\">The research has shown that around one in four French oncologists will adopt a cautious approach, taking all the time necessary to consider whether or not to switch to generic &#039;mAbs&#039;. The number of distrustful rises to one doctor in 3 in Germany, reaching 42-45% in the USA. &quot;The 74-80% of the American oncologists interviewed expects to prescribe the biosimilar versions of ESA and GCsf&quot;, erythropoiesis-stimulating therapies and growth factors, &quot;within a year of market launch&quot;, explains Andrew Merron, director of Biosimilars Advisory Services. <\/p>\n<p><\/font><\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: left; line-height: normal; margin: 0cm 0cm 0pt; text-autospace: ; mso-layout-grid-align: none\"><span style=\"font-family: BookAntiqua; color: #212120; font-size: 12pt; mso-bidi-font-family: BookAntiqua\"><font face=\"Calibri\">Yet &quot;only 54-61% plans to do the same with monoclonal antibody biosimilars.&quot; These products are the real challenge for companies active in the bioequivalent sector, which could see their revenues reduced due to &#039;resistance&#039; from the medical world. However, despite a possible slow take-off, BioTrends expects the market for biosimilar &#039;mAbs&#039; to approach $5 billion by 2021.<\/p>\n<p><\/font><\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: left; margin: 0cm 0cm 10pt\"><i><span style=\"line-height: 115%; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;; color: #212120; font-size: 9pt; mso-bidi-font-weight: bold\">Paola Olgiati \u2013 31 October 2012 \u2013 PharmaKronos<\/span><\/i><span class=\"gd\"><span style=\"line-height: 115%; font-family: &quot;Arial&quot;,&quot;sans-serif&quot;; font-size: 9pt\"><\/p>\n<p><\/span><\/span><\/p>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>La prospettiva di passare dall&#8217;anticorpo monoclonale &#8216;di marca&#8217; alla sua versione equivalente non &egrave; un passaggio automatico per tutti gli oncologi. Anzi, secondo un&#8217;indagine del BioTends Research Group, quando saranno disponibili i biosimilari di farmaci anticancro intelligenti come ad esempio il rituximab (blockbuster della svizzera Roche), una buona percentuale di oncologi potrebbe avere qualche esitazione &hellip;<\/p>","protected":false},"author":1,"featured_media":9846,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[90],"tags":[],"class_list":["post-15696","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fedaiisf-archivio-storico"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts\/15696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/comments?post=15696"}],"version-history":[{"count":0,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts\/15696\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/media\/9846"}],"wp:attachment":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/media?parent=15696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/categories?post=15696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/tags?post=15696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}