{"id":22888,"date":"2015-11-18T18:10:17","date_gmt":"2015-11-18T17:10:17","guid":{"rendered":"http:\/\/www.fedaiisf.it\/?p=22888"},"modified":"2015-11-19T18:04:53","modified_gmt":"2015-11-19T17:04:53","slug":"studio-asl-troppi-farmaci-generici-peggiorano-laderenza-alla-terapia","status":"publish","type":"post","link":"https:\/\/www.fedaiisf.it\/en\/studio-asl-troppi-farmaci-generici-peggiorano-laderenza-alla-terapia\/","title":{"rendered":"Asl study: too many generic drugs worsen adherence to therapy"},"content":{"rendered":"<p><em>Generic drugs are an important alternative to branded drugs, with the same efficacy. But when too many generics are changed for a pathology, the patient complies less with the doctor&#039;s prescriptions, or worsens his adherence to therapy.<\/em><\/p>\n<p><a href=\"http:\/\/www.ecodibergamo.it\/stories\/bergamo-citta\/studio-asl-troppi-farmaci-genericipeggiorano-laderenza-alla-terapia_1152262_11\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">Wednesday 18 November 2015 \u2013 L&#039;ECO DI BERGAMO<\/span><\/a><\/p>\n<p><span class=\"nero\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft\" src=\"http:\/\/www.ondaosservatorio.it\/ondauploads\/2015\/11\/Conferenza_DOC_18_11-580x490.jpg\" alt=\"Conferenza_DOC_18_11\" width=\"508\" height=\"429\" \/>This is in summary the preliminary result of a study conducted in 2 Lombard Local Health Authorities, in Pavia and Bergamo, promoted by the National Observatory on Women&#039;s Health (Onda) in collaboration with Doc Generici.<\/span><\/p>\n<p><span class=\"nero\">The results of the study are obtained from the analysis of over 14,500 patients of the two Local Health Authorities<\/span>. Six therapeutic areas were examined: diabetology, cardiology, dyslipidemia, rheumatology, psychiatry and hypertension. &quot;The goal was to see how the patient behaves when the pharmacist replaces a generic medicine prescribed by the doctor with another equivalent medicine, with the same effectiveness.&quot;<\/p>\n<p><span class=\"nero\">The survey found that &quot;the patient&#039;s adherence to the prescription decreases, with a value equal to 28% if the replacement affects half of the prescriptions<\/span>. In all 6 areas, there was a progressive reduction in adherence after a drug change: on average, if one generic prescription out of two is replaced with an equivalent one, dyslipidemia and diabetes have the highest percentage reduction of adherence (respectively the 48% and <img decoding=\"async\" class=\"alignright\" src=\"http:\/\/www.ondaosservatorio.it\/web\/themes\/onda\/images\/logo-onda-blu.svg\" alt=\"\" \/>the 36%), followed by the area of rheumatology (21%) and psychiatry (19%) and hypertension (10%)\u00bb.<\/p>\n<p>This decline in adherence, the experts conclude, &quot;implies a lower efficacy and safety of therapeutic treatments, with a consequent increase in the risk of complications and a worsening of the patients&#039; health conditions&quot;.<\/p>\n<p>Related news: <a href=\"http:\/\/www.ondaosservatorio.it\/ondauploads\/2015\/11\/4_Sintesi-risultati-per-cartelline.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">Summary of results. Horizontal substitution of generic drug and adherence to therapies<\/span><\/a><\/p>\n<p><a href=\"http:\/\/www.ondaosservatorio.it\/ondauploads\/2015\/11\/3_Interventi-relatori.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">Speech of the speakers at the conference to present the work<\/span><\/a><\/p>\n<p>Wave press release.\u00a0<span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"http:\/\/www.ondaosservatorio.it\/ondauploads\/2015\/11\/2_Comunicato-stampa-18_11_15.pdf\" target=\"_blank\" rel=\"noopener\">Medication adherence: decreases by 28% if half of generic drug prescriptions are replaced with another equivalent<\/a><\/span><\/p>\n<p>Conference programme.\u00a0<a href=\"http:\/\/www.ondaosservatorio.it\/ondauploads\/2015\/11\/invito-conferenza-stampa-18-novembre-2015.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">Generic drug substitution and treatment adherence<\/span><\/a><\/p>\n<p><a href=\"http:\/\/www.ecodibergamo.it\/stories\/bergamo-citta\/i-farmaci-generici-lasl-precisascelta-irrinunciabile-oltre-che-sicura_1152467_11\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">Bergamo. Generic drugs, the ASL specifies &quot;An essential choice, as well as safe&quot;<\/span><\/a><\/p>\n<p><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"http:\/\/www.fedaiisf.it\/en\/la-ue-mette-al-bando-700-farmaci-generici-prodotti-in-india\/\" target=\"_blank\">The EU bans 700 generic medicines produced in India<\/a><\/span><\/p>\n<p><a href=\"http:\/\/salute.ilgiornale.it\/news\/23422\/aderenza-generico-terapia-trattamento-\/1.html\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">Pharmacotherapy: why always use the same medicine<\/span><\/a><\/p>\n<p><a href=\"http:\/\/www.oggitreviso.it\/farmaci-uso-sbagliato-abuso-parte-campagna-dellusl-122146\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">Treviso. Drugs, misuse and abuse: the Local Health Authority campaign starts<\/span><\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>I farmaci generici sono un\u2019importante alternativa ai farmaci di marca, a parit\u00e0 di efficacia. Ma quando si cambiano troppi generici per una patologia il paziente si attiene meno alle prescrizioni del medico, ovvero peggiora la sua aderenza alla terapia. Mercoled\u00ec 18 novembre 2015 &#8211; L&#8217;ECO DI BERGAMO \u00c8 questo in sintesi il risultato preliminare di &hellip;<\/p>","protected":false},"author":4,"featured_media":22894,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[31],"class_list":["post-22888","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-notizie","tag-generici"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts\/22888","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/comments?post=22888"}],"version-history":[{"count":0,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/posts\/22888\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/media\/22894"}],"wp:attachment":[{"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/media?parent=22888"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/categories?post=22888"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fedaiisf.it\/en\/wp-json\/wp\/v2\/tags?post=22888"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}