Are Brand-Name and Generic Drugs Really the Same? The Prescriber Perspective
Laurie Scudder, DNP, NP
Prescribers and patients often voice concerns about the safety and efficacy of generic drugs that are substituted for brand-name drug products. Love ’em or hate ’em, they are with us to stay. The US Food and Drug Administration (FDA) approves a generic substitute if it has proven to be "identical, or bioequivalent, to a brand-name drug in dosage form, safety, strength, route of administration, quality, performance characteristics, and intended use."
The FDA’s Orange Book provides the latest information on generic approvals. Approved generic agents have been demonstrated to have therapeut